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Cyanide Detection using Azo-acylhydrazone in Aqueous Media with High Sensitivity and Selectivity

[ Vol. 12 , Issue. 2 ]

Author(s):

Jing Qi, Jinghan Hu, You Sun and Jianbin Li   Pages 119 - 123 ( 5 )

Abstract:


The cyanide anion (CN) is known to be an extremely toxic anion and can directly lead to the death of human beings in several minutes because it strongly binds cytochrome-c, thereby disrupting the mitochondrial electron-transport chain and causing a decreased oxidative metabolism and oxygen utilization. A colorimetric sensor L1 bearing azosalicylic aldehyde of benzoyl hydrazone was designed and synthesized. The binding property of the sensor L1 with anions such as F, Cl, Br, I, CH3COO, H2PO4, HSO4, ClO4, CN and SCN, was examined by UV-vis and 1H NMR spectra. The result showed that sensor L1 has behaved good selectivity and high sensitivity for CN in DMSO/H2O (5:5, v/v) binary solutions. When CN was added to the solution containing L1, a dramatic color change from colorless to red was observed, while the other anions did not cause noticeable changes. And the detection limits were 1.0×10−5 mol•L-1 and 3.7×10−8 mol•L-1 of CN from visual color changes and UV-vis spectrum changes respectively. Furthermore, test strips based on sensor L1 were fabricated, and sensor L1 could be served as practical colorimetric sensor to detect CN for “in-the-field” measurement. In addition, test strips based on L1 were fabricated, which could serve as a practical colorimetric sensor to detect CN in field measurements or in test kits.

Keywords:

Colorimetric recognition, cyanide detect, anions sensor, test strip.

Affiliation:

College of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou, Gansu, 730070, P.R. China.

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