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A Review on Electrochemical Sensing of Cancer Biomarkers Based on Nanomaterial - Modified Systems

Author(s):

Sorour Salehi Baghbaderani, Parastou Mokarian and Parisa Moazzam*   Pages 1 - 16 ( 16 )

Abstract:


Diagnosis of cancer in the early stages can help to treat efficiently and reduce cancer-related death. Cancer biomarkers can respond to the presence of cancer in body fluids before the appearance of any other symptoms of cancer. The integration of nanomaterials into biosensors as electrochemical platforms offers rapid and sensitive detection for cancer biomarkers. The use of surface-modified electrodes by carbon nanomaterials and metal nanoparticles enhances the performance of electrochemical analysis in biosensing systems through the increase of bioreceptors loading capacity on the surface. In this review, the novel approaches based on nanomaterial-modified systems in point of care diagnostics are highlighted.

Keywords:

Cancer Biomarkers; Electrochemical-based Biosensor, Surface Modified Electrode, Carbon Nanomaterial, Metal Nanoparticles, Diabetes Online Community (DOC)

Affiliation:

Department of Nanotechnology Engineering, Faculty of Advanced Sciences and Technologies, University of Isfahan, Isfahan 81746-73441, Department of Biology, Faculty of Sciences, Central Tehran Branch, Islamic Azad University, Tehran 14676-86831, School of Chemistry, University of New South Wales, Sydney, 2052



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