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Recent Advantages of Mediator Based Chemically Modified Electrodes; Powerful Approach in Electroanalytical Chemistry


Farideh Mousazadeh, Sayed Zia Mohammadi*, Sedighe Akbari, Nastaran Mofidinasab, Mohammad Reza Aflatoonian and Arman Shokooh-Saljooghi   Pages 1 - 25 ( 25 )


Background: Modified electrodes have advanced from the initial studies aimed at understanding electron transfer in films to applications in areas such as energy production and analytical chemistry. This review emphasizes the major classes of modified electrodes with mediators that are being explored for improving analytical methodology. Chemically modified electrodes (CMEs) have been widely used to counter the problems of poor sensitivity and selectivity faced in bare electrodes. We have briefly reviewed the organometallic and organic mediators that have been extensively employed to engineer adapted electrode surfaces for the detection of different compounds. Also, the characteristics of the materials that improve the electrocatalytic activity of the modified surfaces are discussed.

Objective: Improvement and promotion of pragmatic CMEs have generated a diversity of novel and probable strong detection prospects for electroanalysis. While the capability of handling the chemical nature of the electrode/solution interface accurately and creatively increases , it is predictable that different mediators-based CMEs could be developed with electrocatalytic activity and completely new applications be advanced.


Chemically modified electrodes, electrocatalysis, electrochemical sensors, organometallic mediators, organic mediators, review.


School of Public Health, Bam University of Medical Sciences, Bam, Department of Chemistry, Payame Noor University, Tehran, Islamic Azad University, Shahrbabak Branch, Shahrbabak, School of Public Health, Bam University of Medical Sciences, Bam, Research Center for Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Department of Chemistry, Shahid Bahonar University, Kerman

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