Quanxia Lyu, Shu Gong, Jennifer M. Dyson and Wenlong Cheng* Pages 1 - 16 ( 16 )
Background: Soft wearable electrochemical biosensors are attracting increasing attention over the past several years due to their potential for non-invasive personalized health monitoring in real-time and in-situ.
Objective: Herein, we cover the design, fabrication, and applications of soft electrochemical sensing systems. Firstly, we describe key design requirements for fabricating the mechanically compliant electrochemical biosensors. This is followed by a narration of typical sensor configurations and the detecting methodologies. Next, on-body soft electrochemical biosensing and cell/tissue-based “wearable” sensing applications are summarized. Detection of key biochemical markers, including metabolites (glucose, lactate, uric acid and ethanol), electrolytes (Na+ and K+), nutrients (vitamin C), hormones (cortisol) and proteins (TNF-α), as well as cellular signalling molecules (nitric oxide, hydrogen peroxide and serotonin), is the focus of the discussion in this review.
Conclusion: We conclude the review with discussions on future opportunities and challenges of the soft and wearable electrochemical biosensors.
Soft wearable electronics, biosensors, nanomaterials, stretchable, electrochemistry, review.
Department of Chemical Engineering, Monash University, Clayton, Victoria 3800, Department of Chemical Engineering, Monash University, Clayton, Victoria 3800, Faculty of Engineering, Monash Institute of Medical Engineering (MIME), Monash University, Clayton, Victoria 3800, Department of Chemical Engineering, Monash University, Clayton, Victoria 3800